VASODILATORS AND α-ADRENOCEPTOR ANTAGONISTS IN HYPERTENSION AND HEART FAILURE
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چکیده
منابع مشابه
Aldosterone antagonists in hypertension and heart failure.
Spironolactone, a competitive aldosterone receptor antagonist (ARA), has traditionally been the treatment of first choice in idiopathic hyperaldosteronism (IHA) and for preoperative management of aldosterone producing adenoma (APA). Spironolactone is partially absorbed, is extensively metabolized mainly by the liver and its therapeutic properties are attributable to active metabolite canrenone....
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1981
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1981.tb00292.x